US Society for Neuroscience: Microvitae presents results on brain polymer electrodes

Thierry Herve -- 2012-01-06 19:01:15

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New flexible neuronal probes for long-term experiments
Thomas Doublet a, b,c, Dion Khodagholy b, Esma Ismailovab, Pascale Quilichinia, Pierre Leleux a, b,c, Antoine Ghestema, Thierry Hervec, George Malliarasb, Christophe Bernarda
a Laboratoire Epilepsies et Cognition, INSERM U 751, Faculté de médecine secteur Timone, 27 bd Jean Moulin, 13385 Marseille cedex 05
b Centre Microélectronique de Provence, Ecole Nationale Supérieure des Mines de Saint-Etienne, 880 route de Mimet, 13541 Gardanne
c Microvitae, Ecole Nationale Supérieure des Mines de Saint-Etienne, 880 route de Mimet, 13541 Gardanne


 


Understanding of neuronal networks can be helped by the development of new flexible probes. The conventional neuronal probes, with multiple recording sites, allow recording of neuronal activities on freely moving animals. However, the rigid nature of those probes, implantable or designed for surface Electrocorticogram (ECoG) recordings (E-probe), increases the decline of the recorded signal quality with time.
We developed new flexible implantable and E-probe microelectrodes to minimize the lesions and maximize the recording interface with the tissue. Furthermore, the conducting polymer used as electrode site increases the signal to noise ratio by comparison to gold.
Those conducting polymer and insulator layers provide good biocompatibility and a high mechanical flexibility.
These new probes increase the quality and duration of neuronal signals for long-term experiments.

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Oct 2011: Paper in Applied Physics Letters

Thierry Herve -- 2011-10-21 10:20:45

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High speed and high density organic electrochemical transistor arrays


Appl. Phys. Lett. 99, 163304 (2011)

Tags: epilepsy, electrode, ocnductive polymer, brain, monitoring

OCT 2011 Microvitae participates 2011 BMES Annual Conference (BioMedical Engineering Society)Hartford USA

Thierry Herve -- 2011-10-12 17:10:27

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High Speed and High Density Organic Electrochemical Transistor Arrays

Tags: epilepsy, polyper transistor, electrode

JULY 2011: a paper to be publish soon in "Advanced Materials"

Thierry Herve -- 2011-10-12 17:10:17

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Highly Conformable Conducting Polymer Electrodes for In Vivo Recordings. Adv. Mater. 36, H268 (2011)

Tags: epilepsie, electrode, conductive polymer, brain, monitoring

AUG 2011: a paper published in International Journal of Nanotechnology

Thierry Herve -- 2011-10-12 15:45:21

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Thanks to extensive research on brain devices based on cooperation between BEL Lab (BioELectronique lab of Ecole Nationale Supérieure des Mines de St Etienne) and U INSERM 751 located in la Timone University Hospital of Marseille, Microvitae publishes advances on conductive polymer probes developpement for brain activity recordings.


 


"Plastic neuronal probes for implantation in cortical and subcortical areas of the rat brain"


International Journal of Nanotechnology. Volume 8, Nos 10-12 (2011)

Tags: epilepsy, electrode, conductive polymer, brain, monitoring